import os
import requests
import urllib.request
import re

import hashlib

def upto_openload(files):

    dir0 = str(os.getcwd()).replace('\\', '/')
    os.chdir(dir0)

    sha1 = hashlib.sha1()

    BLOCKSIZE = 65536
    with open(files, 'rb') as afile:
        buf = afile.read(BLOCKSIZE)
        while len(buf) > 0:
            sha1.update(buf)
            buf = afile.read(BLOCKSIZE)

    sha1_hash = sha1.hexdigest()

    url = "https://api.openload.co/1/file/ul?login={login}&key={key}&sha1={sha1}".format(
        login='xxxxxxx',
        key='xxxxxx',
        sha1=sha1_hash,
    )

    p = {
        'url': url,
        'headers': {
            'User-Agent': 'Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/58.0.3029.110 Safari/537.36',
        }
    }
    r = requests.get(url=p['url'], headers=p['headers'])
    j = r.json()

    print(j)
    upload_link = j['result']['url']
    print(upload_link)


    files = {'file': open(files, 'rb')}

    r = requests.post(upload_link, files=files)
    j = r.json()
    print(j)
    dl=j['result']['url']
    return dl


files = 'test01.txt'
dl=upto_openload(files)
print(dl)

https://api.openload.co/1/file/ul?login={login}&key={key}&folder={folder}&sha1={sha1}&httponly={httponly}

200 (OK)
Content-Type: application/json

{
    "status": 200,
    "msg": "OK",
    "result": {
        "url": "https://13abc37.example.com/ul/fCgaPthr_ys",
        "valid_until": "2015-01-09 00:02:50"
    }
}